It sounds like you want to add columns for all new data (not row) so you would likely need to determine the width of your spreadsheet with . Parameters: filename : File path or existing ExcelWriter (Example: '/path/to/file.xlsx') df : dataframe to save to workbook sheet_name : Name of sheet which will contain DataFrame. Note that, I still need multiple sheets for different dataframe, but also multiple dataframes on each sheet. To summarize, you use pandas’ ExcelWriter to create a work in progress workbook, while making use of the data of an existing workbook. Create an Excel Sheet import pandas as pd writer = pd.ExcelWriter('demo.xlsx', engine='xlsxwriter') writer.save(). df . ... ExcelWriter (FilePath, engine = 'openpyxl') A data frame can be added as a new sheet to an existing excel sheet. I have never used Pandas or messed with excel files before but I can tell you this much; to_excel() is expecting type ExcelWriter ie: # Specify a writer writer = pd.ExcelWriter('example.xlsx', engine='xlsxwriter') # Write your DataFrame to a file yourData.to_excel(writer, 'Sheet1') # … Pandas Excel writer update existing excel file [closed] ... #Create a Pandas Excel writer using XlsxWriter as the engine. writer = pandas.ExcelWriter('Masterfile.xlsx') data_filtered.to_excel(writer, "Main", cols=['Diff1', 'Diff2']) writer.save() Masterfile.xlsx already consists of number of different tabs. Then, write some other data to a new worksheet, save the file and voilà, you have just added a new worksheet to your workbook. Create an Excel Sheet import pandas as pd writer = pd.ExcelWriter('demo.xlsx', engine='xlsxwriter') writer.save(). I tried the pandas.ExcelWriter() method, but each dataframe overwrites the previous frame in the sheet, instead of appending. Is it possible? Python / Leave a Comment / By Farukh Hashmi. Parameters: filename : File path or existing ExcelWriter (Example: '/path/to/file.xlsx') df : dataframe to save to workbook sheet_name : Name of sheet which will contain DataFrame. I'm using excelwriter with engine openpyxl to add a sheet of data to an existing excel. For this operation, the library required is openpyxl. Is anyone able to tell me what am I missing? I'm using excelwriter with engine openpyxl to add a sheet of data to an existing excel. Pandas correctly writes to "Main" sheet, unfortunately it also deletes all other tabs. Add new sheet to excel using pandas. Hello, I am trying to add a dataframe to an existing sheet. Thank you! Reference How to save a new sheet in an existing excel file, using Pandas? However, it does not yet contain "Main". This code will create a new demo.xlsx file with a default sheet named Sheet1. 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